Error
Your session has expired. Please click "Refresh" to refresh the page.
Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
Newsletter Sign Up
NR1D2
Overview
Synonyms
BD73 ; EAR-1R ; NR1D2 ; NR1D2-B ; Nr1d2 ; REV-ERBB ; RVR ; Rev-Erb beta 2 ; Rev-erb ; Rev-erb beta ; Rev-erb-beta ; V-erbA-related protein 1-related ; nr1d2b ; nuclear receptor Rev-ErbA beta variant 1 ; nuclear receptor Rev-ErbA beta variant 2 ; nuclear receptor subfamily 1 group D member 2 ; orphan nuclear hormone receptor BD73 ; orphan nuclear receptor RVR ; rev erb beta 2 ; rev-erb alpha-related receptor ; rev-erb-beta ; rev-erba-alpha-related receptor ; reverbb ; reverbb2 ; zgc:92019
NURSA Name
Rev-Erb β
Official Symbol
NR1D2
No records found.
Description
RevErb-β, along with RevErb-α, is a member of the orphan RevErb subfamily of the nuclear receptor superfamily of transcription factors. Both members of this family are widely expressed during development and adult life, indicating broad roles in cell proliferation and physiology. RevErb-β is expressed at low to moderate levels in most physiological systems, including the endocrine system, gastrointestinal system, reproductive system, cardiopulmonary system and metabolic tissues, with particularly high expression levels in the central nervous system (CNS), including the hypothalamus, spinal cord, olfactory bulb, corpus striatum, cerebrum and cerebellum.
Original References:
Dumas B, Harding HP, Choi HS, Lehmann KA, Chung M, Lazar MA and Moore DD (1994) A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb. Mol. Endocrinol. 8 996-1005 View Abstract | View PubMed
Ortholog
Gene
RNA
Protein
GO Terms
Crystal Structures
Post-Translational Modifications
Protein-Protein Interactions
Targeting miRNAs
Pathways
Pharmacogenomics
Datasets
Reagents
Diseases
Clinical Trials
Animal Models
Ligands
Drugs
Literature