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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
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NR2E1
Overview
Synonyms
CG9019 ; CG9019-PA ; CG9019-PB ; DSF ; Dmel\CG9019 ; Drosophila terminal/gap gene tailless homolog ; Dsf ; Mtl1 ; Mtll ; NR2D1 ; NR2E1 ; NR2E4 ; Nr2e1 ; TLL ; TLX ; Tlx ; XTLL ; dsf ; dsf-PA ; dsf-PB ; fc30e03 ; fc39f12 ; fierce ; frc ; nhr-67 more...
Synonyms
CG9019; CG9019-PA; CG9019-PB; DSF; Dmel\CG9019; Drosophila terminal/gap gene tailless homolog; Dsf; Mtl1; Mtll; NR2D1; NR2E1; NR2E4; Nr2e1; TLL; TLX; Tlx; XTLL; dsf; dsf-PA; dsf-PB; fc30e03; fc39f12; fierce; frc; nhr-67; nr2e1; nuclear receptor TLX; nuclear receptor subfamily 2 group E member 1; protein tailless homolog; tailes-related receptor; tailless; tailless homolog; tll; wu:fc30e03; wu:fc39f12; zgc:100991
NURSA Name
Tailless homolog
Official Symbol
NR2E1
No records found.
Description
TLX is an orphan member of the nuclear receptor superfamily of transcription factors. TLX is expressed exclusively in the cerebrum and corpus striatum. Targeted disruption (knockout) of TLX results in defects in the central nervous system (CNS) in learning and behavior, and in vision.
Original References:
Jackson A, Panayiotidis P and Foroni L (1998) The human homologue of the Drosophila tailless gene (TLX): characterization and mapping to a region of common deletion in human lymphoid leukemia on chromosome 6q21. Genomics 50 34-43 View Abstract | View PubMed
Ortholog
Gene
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