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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
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Rosi
Overview
Name
Rosiglitazone
Synonyms
BRL49653 ; Rosi ; Rosiglitazone
ChEBI ID
IUPHAR ID
PubChem ID
CAS Registry ID
122320-73-4
Jmol
Not available
Description
Roziglitazone is a member of the insulin-sensitizing thiazolidinedione class of drugs and a selective agonist for peroxisome proliferator-activated receptor-γ (PPARγ), a member of the PPAR subfamily of the nuclear receptor superfamily of transcription factors. While it is effective in establishing glycemic control in patients with type II diabetes, clinical trials have indicated an increased incidence in myocardial infarction.
Pathways
Pharmacogenomics
Nuclear Receptors
Datasets
Pharmacology
Carriers
Enzymes
Targets
Transporters
Literature