NURSA | L165041 - L-165041

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Overview

Name

L-165041

Synonyms

L-165041 ; L165041 ;

ChEBI ID

353642

IUPHAR ID

2691

PubChem ID

6603901

CAS Registry ID

79558-09-1

Jmol

Not available

Description

L-165041 is a selective agonist of peroxisome proliferator-activated receptor-δ (PPARδ), a member of the nuclear receptor superfamily of transcription factors. It has been shown to inhibit angiotensin II-induced cardiac hypertrophy in a cell culture model.

Pathways

Name	Source
Name	Source

Pharmacogenomics

Dosing Guideline	Summary
Dosing Guideline	Summary

Drug Label	Summary	Agency Approval	PGx level
Drug Label	Summary	Agency Approval	PGx level

Type(s)	Gene(s)	Clinical Variant	Chemical(s)	Phenotypes	Race	Clinical Annotations
Type(s)	Gene(s)	Clinical Variant	Chemical(s)	Phenotypes	Race	Clinical Annotations

Nuclear Receptors

Symbol	Description
No nuclear receptors are available for this ligand.

Find genes regulated by this molecule using Transcriptomine, a tool created by NURSA for mining tissue-specific NR, NR ligand, and coregulator transcriptomes based on published genome wide transcriptional profiling experiments in the field of nuclear receptor signaling.

Note: This link will take you to a Transcriptomine query page. For website performance, only results containing 500 fold changes or fewer can be viewed in your browser. If these preset parameters retrieve more than 500 fold changes, you will have the option to download the results as an Excel file or adjust the query parameters (e.g. fold change size, tissue/cell line) to reduce the number of results so that you can view them in your web browser.

Literature