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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
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CPromZ
Overview
Name
Chlorpromazine
Synonyms
CPromZ ; Chlorpromazine ;
ChEBI ID
IUPHAR ID
PubChem ID
CAS Registry ID
50-53-3
Jmol
Not available
Description
The products of the cytochrome P450 (CYP) genes play an important role in the detoxification of xenobiotics and environmental contaminants, and many foreign chemicals or xenobiotics can induce their expression. Chlorpromazine is an antipsychotic drug that has been shown to induce CYP2B family genes through the constitutive androstane receptor (CAR), a member of the nuclear receptor superfamily of transcription factors.
Pathways
Pharmacogenomics
Nuclear Receptors
Datasets
Pharmacology
Carriers
Enzymes
Targets
Transporters
Literature