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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
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AGN194204
Overview
Name
AGN194204
Synonyms
AGN194204 ;
ChEBI ID
IUPHAR ID
PubChem ID
CAS Registry ID
260262-39-3
Jmol
Not available
Description
Rexinoids are a class of compounds that selectively bind to and activate members of the retinoid X receptor (RXR) subfamily of the nuclear receptor superfamily of transcription factors. AGN194204 is a retinoid X receptor (RXR)-selective agonist (rexinoid) which has been shown to reduce basal endogenous glucose production and to act as an insulin sensitizer, as well as suppressing pancreatic cancer cell proliferation.
Pathways
Pharmacogenomics
Nuclear Receptors
Datasets
Literature