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Nuclear Receptor Signaling Atlas
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SF3A1
Overview
Synonyms
1200014H24Rik ; 5930416L09Rik ; AI159724 ; AT1G14640 ; CG16941 ; CG16941-PA ; Dmel\CG16941 ; PRP21 ; PRPF21 ; SAP 114 ; SAP114 ; SF3A1 ; SF3A120 ; SF3a1 ; SF3a120 ; Sf3a1 ; T5E21.18 ; T5E21_18 ; pre-mRNA processing 21 ; pre-mRNA splicing factor SF3a (120 kDa subunit) ; prp-21 ; sf3a1 ; si:dz150f13.2 ; spliceosome-associated protein 114 ; splicing factor 3 subunit 1 more...
Synonyms
1200014H24Rik; 5930416L09Rik; AI159724; AT1G14640; CG16941; CG16941-PA; Dmel\CG16941; PRP21; PRPF21; SAP 114; SAP114; SF3A1; SF3A120; SF3a1; SF3a120; Sf3a1; T5E21.18; T5E21_18; pre-mRNA processing 21; pre-mRNA splicing factor SF3a (120 kDa subunit); prp-21; sf3a1; si:dz150f13.2; spliceosome-associated protein 114; splicing factor 3 subunit 1; splicing factor 3A subunit 1; splicing factor 3a, subunit 1; splicing factor 3a, subunit 1, 120kDa; wu:fc38e01; wu:fc50a11; wu:fj37c05; zgc:65786
NURSA Name
Splicing factor 3a, subunit 1, 120kDa
Official Symbol
SF3A1
No records found.
Description
Splicing factor SF3A subunit 1 was characterized as a component of the ER-AF1 complex to potentiate human ERα-mediated transactivation as well as RNA splicing through interaction with Ser118 phosphorylated receptor, suggesting that MAPK-mediated cross-talk between growth factor and estrogen-signaling pathways can modulate RNA splicing through the phosphorylation-dependent interaction between ERα and a component of the spliceosome complex.
Original References:
Brosi R, Hauri HP and Krämer A (1993) Separation of splicing factor SF3 into two components and purification of SF3a activity. J. Biol. Chem. 12 17640-6 View Abstract | View PubMed
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