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Nuclear Receptor Signaling Atlas
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MN1
Overview
Synonyms
AA003644 ; AA009236 ; MGCR ; MGCR1 ; MGCR1-PEN ; MN1 ; Mn1 ; RGD1565571 ; dJ353E16.2 ; im:7154980 ; meningioma (translocation balanced) ; meningioma chromosome region 1 ; mn1b ; probable tumor suppressor protein MN1 ; si:ch211-223p9.1
NURSA Name
Meningioma-1
Official Symbol
MN1
No records found.
Description
MN1 is a nuclear protein first identified as a gene disrupted in some meningiomas and leukemias. It was initally identified as a coregulator for the nuclear receptor superfamily of transcription factors based on its role as a coactivator for the vitamin D receptor (VDR),
Original References:
Sutton AL, Zhang X, Ellison TI and Macdonald PN (2005) The 1,25(OH)2D3-regulated transcription factor MN1 stimulates vitamin D receptor-mediated transcription and inhibits osteoblastic cell proliferation. Mol. Endocrinol. 19 2234-44 View Abstract | View PubMed
Ortholog
Gene
RNA
Protein
GO Terms
Crystal Structures
Post-Translational Modifications
Protein-Protein Interactions
Targeting miRNAs
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Pharmacogenomics
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