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Nuclear Receptor Signaling Atlas
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SFPQ
Overview
Synonyms
100 kDa DNA-pairing protein ; 1110004P21Rik ; 2810416M14Rik ; 5730453G22Rik ; 9030402K04Rik ; AU021830 ; BEST:LD09360 ; CG10328 ; CG10328-PA ; CG10328-PB ; D4Ertd314e ; DNA-binding p52/p100 complex, 100 kDa subunit ; Dmel\CG10328 ; Gm12940 ; LD09360 ; NonO/p54nrb homolog ; OTTMUSG00000009329 ; POMP100 ; PSF ; PTB-associated splicing factor ; PTB-associated-splicing factor ; REP1 ; SFPQ ; Sfpq ; Z more...
Synonyms
100 kDa DNA-pairing protein; 1110004P21Rik; 2810416M14Rik; 5730453G22Rik; 9030402K04Rik; AU021830; BEST:LD09360; CG10328; CG10328-PA; CG10328-PB; D4Ertd314e; DNA-binding p52/p100 complex, 100 kDa subunit; Dmel\CG10328; Gm12940; LD09360; NonO/p54nrb homolog; OTTMUSG00000009329; POMP100; PSF; PTB-associated splicing factor; PTB-associated-splicing factor; REP1; SFPQ; Sfpq; Z; gizzard PTB-associated splicing factor; hPOMp100; hm:zeh0027; no-on transient A gene; no-on transient A-like; nonA 1; nonA-1; nonA-l; nonA-l-PA; nonA-l-PB; polypyrimidine tract binding protein associated; polypyrimidine tract-binding protein-associated splicing factor; polypyrimidine tract-binding protein-associated-splicing factor; predicted gene Z; sfpq; splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); splicing factor proline/glutamine rich (polypyrimidine tract-binding protein-associated); splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated); splicing factor, proline- and glutamine-rich; wis; wu:fa11h12; wu:fd10f03; zgc:85935
NURSA Name
Polypyrimidine tract-binding protein-associated splicing factor
Official Symbol
SFPQ
No records found.
Description
PSF is a RNA recognition domain-containing protein that forms a heterodimer with another nuclear receptor coregulator, p54nrb, that has roles in transcription-splicing coupling and DNA unwinding.
Original References:
Patton JG, Porro EB, Galceran J, Tempst P and Nadal-Ginard B (1993) Cloning and characterization of PSF, a novel pre-mRNA splicing factor. Genes Dev. 7 393-406 View Abstract | View PubMed
Mathur M, Tucker PW and Samuels HH (2001) PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors. Mol. Cell. Biol. 21 2298-311 View Abstract | View PubMed
Dong X, Shylnova O, Challis JR and Lye SJ (2005) Identification and characterization of the protein-associated splicing factor as a negative co-regulator of the progesterone receptor. J. Biol. Chem. 24 13329-40 View Abstract | View PubMed
Ortholog
Gene
RNA
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