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Nuclear Receptor Signaling Atlas
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DCLK1
Overview
Synonyms
1700113D08Rik ; 2810480F11Rik ; AI836758 ; CL1 ; CLICK-I beta ; CLICK1 ; Click-I ; Cpg16 ; DCAMKL1 ; DCDC3A ; DCLK ; DCLK1 ; Dcamkl1 ; Dcl ; Dclk ; Dclk1 ; PEPKR2 ; T12C24.32 ; T12C24_32 ; doublecortin and CaM kinase-like 1 ; doublecortin and calcium/calmodulin-dependent protein kinase-like 1 ; doublecortin domain-containing protein 3A ; doublecortin-like and CAM kinase-like 1 ; mKIAA0369 ; phosphoenolpyruvate carboxylase-related kinase 2 more...
Synonyms
1700113D08Rik; 2810480F11Rik; AI836758; CL1; CLICK-I beta; CLICK1; Click-I; Cpg16; DCAMKL1; DCDC3A; DCLK; DCLK1; Dcamkl1; Dcl; Dclk; Dclk1; PEPKR2; T12C24.32; T12C24_32; doublecortin and CaM kinase-like 1; doublecortin and calcium/calmodulin-dependent protein kinase-like 1; doublecortin domain-containing protein 3A; doublecortin-like and CAM kinase-like 1; mKIAA0369; phosphoenolpyruvate carboxylase-related kinase 2; serine/threonine-protein kinase DCLK1
NURSA Name
Doublecortin-like
Official Symbol
DCLK1
No records found.
Description
DCL is a protein kinase containing two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization. DCL was shown to control subcellular localization by the glucocorticoid receptor (GR), a member of the nuclear receptor transcription factor superfamily, and to act as a corepressor of GR function.
Original References:
Fitzsimons CP, Ahmed S, Wittevrongel CF, Schouten TG, Dijkmans TF, Scheenen WJ, Schaaf MJ, de Kloet ER and Vreugdenhil E (2008) The microtubule-associated protein doublecortin-like regulates the transport of the glucocorticoid receptor in neuronal progenitor cells. Mol. Endocrinol. 22 248-62 View Abstract | View PubMed
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