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Nuclear Receptor Signaling Atlas
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MTA2
Overview
Synonyms
AW550797 ; MTA1-L1 protein ; MTA1L1 ; MTA2 ; Mata1l1 ; Metastasis-associated 1-like 1 ; Mta1l1 ; Mta2 ; PID ; fd61b05 ; metastais-associated gene family, member 2 ; metastasis -associated gene 1-like 1 ; metastasis associated 1-like 1 ; metastasis associated gene family, member 2 ; metastasis-associated 1-like 1 ; metastasis-associated gene family, member 2 ; metastasis-associated protein 2 ; metastasis-associated protein MTA2 ; mmta2 ; mta2 ; p53 target protein in deacetylase complex ; wu:fd61b05 ; wu:fi29g02 ; zgc:63487
NURSA Name
Metastais-associated gene family, member 2
Official Symbol
MTA2
No records found.
Description
The metastasis-associated family of proteins, including MTA1 and MTA2, have been shown to be involved in breast cancer progression. MTA2 has been shown to repress ER-α activity, potentially through its associated histone deacetylase activity.
Original References:
Xue Y, Wong J, Moreno GT, Young MK, Côté J and Wang W (1998) NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities. Mol. Cell 2 851-61 View Abstract | View PubMed
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