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Nuclear Receptor Signaling Atlas
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Analysis of the R1881-regulated transcriptome in gedunin-treated LNCaP cells
Overview
Dataset Name :
Analysis of the R1881-regulated transcriptome in gedunin-treated LNCaP cells
Description :
Human LNCaP prostate cancer cells were treated for 24 h: (1) with or without 1 nM R1881; or (2) with 1 nM R1881 or 1 nM R1881 + gedunin, a tetranortriterpenoid hsp90 inhibitor isolated from the Indian neem tree Azadirachta indica.
Dataset Type :
Transcriptomic
Release Date :
March 28, 2015
DOI :
10.1621/vWp6CUbniU
Version :
This is Version 1.0 of an annotated derivative of the original dataset, which can be found in GSE5508
Dataset Citation :
Hieronymus H and Golub TR (2006) Analysis of the R1881-regulated transcriptome in gedunin-treated LNCaP cells., v1.0.NURSA Datasets. dx.doi.org/10.1621/vWp6CUbniU
Download Citation :

Associated Article :
Hieronymus H, Lamb J, Ross KN, Peng XP, Clement C, Rodina A, Nieto M, Du J, Stegmaier K, Raj SM, Maloney KN, Clardy J, Hahn WC, Chiosis G and Golub TR (2006) Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell 10 321-30 View Abstract | View PubMed

Experiments

There are 2 Experiments for this dataset

  • 1 | R1881 vs Veh
  • 2 | Gedunin vs Veh (R1881)
Gene List
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Symbol Fold Change P-Value Query in Transcriptomine
Symbol Fold Change P-Value Query in Transcriptomine
Experiment Information
Name : R1881 vs Veh
Description :

Human LNCaP prostate cancer cells were treated with or without 1 nM R1881 for 24 h.

Tissue/Cell line : epithelium, LNCaP cells
Species : Human
Regulatory Information
Name Duration of Treatment Concentration
R1881 24 hour 1 nanomolar
Related Datasets
Datasets related by:
  • Regulatory Molecule
  • RNA Source

NameDOI
Analysis of the R1881-regulated transcriptome in histone deacetylase inhibitor-treated LNCaP prostate cancer cells 10.1621/NwJaVv9VfA
Analysis of the R1881-regulated transcriptome in histone deacetylase-depleted LNCaP prostate cancer cells 10.1621/r7Go7nAePv
Analysis of the ELK and R1881-dependent transcriptomes in LNCaP prostate cancer cells 10.1621/xZngfuhLwA
Analysis of the R1881-regulated transcriptome in celastrol-treated LNCaP cells 10.1621/aWNqvAebS2
Analysis of the UXT and R1881 dependent transcriptomes in LNCaP prostate cancer cells 10.1621/gZmIbonYZ2
Analysis of the androgen receptor (AR) and R1881-regulated transcriptomes in LNCaP cells 10.1621/2ooIJnQYTu
Analysis of the androgen receptor (AR)-dependent transcriptome in PC3 prostatic carcinoma cells 10.1621/wGxM43bqxz
Comparative analysis of the wild-type and CR7 mutant androgen receptor (AR)-regulated metabolomes in LNCaP cells 10.1621/F3qO0nGxC7
Time course analysis of the R1881-regulated transcriptome in the human LNCaP prostate cancer cell line 10.1621/43PVad2d8U
Time course transcriptomic analysis of R1881-treated LNCaP cells 10.1621/uSlDnYWdEw
Additional Information