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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
P/CAF
Overview
Synonyms
A930006P13Rik ; AI461839 ; AW536563 ; CAF ; CREBBP-associated factor ; KAT2B ; Kat2b ; LOC698283 ; P ; P/CAF ; PCAF ; Pcaf ; histone acetylase PCAF ; histone acetyltransferase KAT2B ; histone acetyltransferase PCAF ; kat2b ; lysine acetyltransferase 2B ; p/CAF ; p300/CBP-associated factor ; pcaf ; si:ch211-1j13.2 ; zgc:161980
NURSA Name
p300/CBP-associated factor
NURSA Symbol
P/CAF
Description
P/CAF is an acetyltransferase that was originally characterized as an interacting partner of the transcriptional co-integrators CBP and p300. It has been shown to potentiate signaling by nuclear receptors.
Original References:
Blanco JC, Minucci S, Lu J, Yang XJ, Walker KK, Chen H, et al. (1998) The histone acetylase PCAF is a nuclear receptor coactivator. Genes Dev. 12 1638-51 View Abstract | View Pubmed
Yang XJ, Ogryzko VV, Nishikawa J, Howard BH, Nakatani Y, (1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 126 319-24 View Abstract | View Pubmed
Human
Gene
RNA
Protein
GO Terms
Crystal Structures
Post-Translational Modifications
Protein-Protein Interactions
Targeting miRNAs
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Literature

Last updated: January 31, 2014