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Nuclear Receptor Signaling Atlas
A research resource for the nuclear receptor signaling community
P/CAF
Last updated January 31, 2014
Overview
NURSA Name
p300/CBP-associated factor
NURSA Symbol
P/CAF
Synonyms
A930006P13Rik; AI461839; AW536563; CAF; CREBBP-associated factor; KAT2B; Kat2b; LOC698283; P; P/CAF more...
Synonyms
A930006P13Rik; AI461839; AW536563; CAF; CREBBP-associated factor; KAT2B; Kat2b; LOC698283; P; P/CAF; PCAF; Pcaf; histone acetylase PCAF; histone acetyltransferase KAT2B; histone acetyltransferase PCAF; kat2b; lysine acetyltransferase 2B; p/CAF; p300/CBP-associated factor; pcaf; si:ch211-1j13.2; zgc:161980
Description
P/CAF is an acetyltransferase that was originally characterized as an interacting partner of the transcriptional co-integrators CBP and p300. It has been shown to potentiate signaling by nuclear receptors.
Original References:
Blanco JC,Minucci S,Lu J,Yang XJ,Walker KK,Chen H, et al. (1998) The histone acetylase PCAF is a nuclear receptor coactivator. Genes Dev. 12 1638-51 View Abstract | View Pubmed
Yang XJ,Ogryzko VV,Nishikawa J,Howard BH,Nakatani Y, (1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 126 319-24 View Abstract | View Pubmed
View Pubmed

Abstract

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