REV-ERB-β

Browse nuclear receptors
|
 
Name
Rev-Erb β
Symbol
REV-ERB-β
NRNC Symbol
NR1D2

Overview

RevErb-β, along with RevErb-α, is a member of the orphan RevErb subfamily of the nuclear receptor superfamily of transcription factors. Both members of this family are widely expressed during development and adult life, indicating broad roles in cell proliferation and physiology.

Expression

RevErb-β is expressed at low to moderate levels in most physiological systems, including the endocrine system, gastrointestinal system, reproductive system, cardiopulmonary system and metabolic tissues, with particularly high expression levels in the central nervous system (CNS), including the hypothalamus, spinal cord, olfactory bulb, corpus striatum, cerebrum and cerebellum.

View full NURSA RevErb-β expression dataset


 Nuclear Receptor Pages User Guide (updated Oct 2008)

At a Glance
Phylogeny
Class
TR/RAR/PPAR/VDR-like receptors
NRNC Group
Rev-Erb (NRD, E75)

Nomenclature
nuclear receptor subfamily 1, group D, member 2 (NR1D2); orphan nuclear receptor NR1D2 (ONR1D2); v-erbA related protein EAR-1-related (EAR-1R); orphan nuclear hormone receptor BD73 (BD73); Rev-Erb β (REV-ERBβ)

Primary References
Dumas B, Harding HP, Choi HS, Lehmann KA, Chung M, Lazar MA and Moore DD (1994) A new orphan member of the nuclear hormone receptor superfamily closely related to Rev-Erb. Mol Endocrinol 8, 996-1005. View Abstract | View Mol Endocrinol

My NURSA
Username
Password
Remember me
Forgot your password? Get it here.
Need to register? Click here.
Molecule Navigator
Receptors
Coregulators
Ligands
Select a range
1-E    F-L    M-Q    R-Z   
Select a specific molecule
Feedback

Questions? Comments?
Send Feedback Here

 
© 2003 - 2010 NURSA, The Nuclear Receptor Signaling Atlas.