p300

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Name
E1A binding protein p300
Symbol
p300
p300, and the closely related protein CBP, are transcriptional coregulators which mediate the functions of multiple transcription factors, including members of the nuclear receptor superfamily, in a wide variety of developmental and physiological processes.

 Coregulator Pages User Guide (updated Oct 2008)

At a Glance
Nomenclature
E1A binding protein p300 (p300)

Primary References
Chakravarti D, LaMorte VJ, Nelson MC, Nakajima T, Schulman IG, Juguilon H, Montminy M and Evans RM (1996) Role of CBP/P300 in nuclear receptor signalling. Nature 383, 99-103. View Abstract | View PubMed
Eckner R, Ewen ME, Newsome D, Gerdes M, DeCaprio JA, Lawrence JB and Livingston DM (1994) Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev 8, 869-84. View Abstract | View PubMed

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