MBF-1

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Name
Multiprotein bridging factor-1
Symbol
MBF-1
MBF-1 was originally described for its ability to potentiate signaling by the orphan nuclear receptor FTZ-F1. It has been characterized since as a coregulator of nuclear receptors involved in steroidogenesis and lipid metabolism.

 Coregulator Pages User Guide (updated Oct 2008)

At a Glance
Nomenclature
Multiprotein bridging factor-1 (MBF-1); Endothelial differentiation-related factor 1 (EDF1)

Primary References
Kabe Y, Goto M, Shima D, Imai T, Wada T, Morohashi K, Shirakawa M, Hirose S and Handa H (1999) The role of human MBF1 as a transcriptional coactivator. J Biol Chem 274, 34196-202. View Abstract | View PubMed
Dragoni I, Mariotti M, Consalez GG, Soria MR and Maier JA (1998) EDF-1, a novel gene product down-regulated in human endothelial cell differentiation. J Biol Chem 273, 31119-24. View Abstract | View PubMed

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