SUN-CoR

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Name
Small unique nuclear receptor corepressor, nuclear DNA-binding protein
Symbol
SUN-CoR

Overview

SUN-CoR is a small, highly basic nuclear protein that is induced during adipocyte and myogenic differentiation. It was originally identified as a nuclear receptor coregulator based on its abiliy to function as a corepressor for the nuclear receptors thyroid hormone receptor (TR) and RevErb.

Expression

SUN-CoR is expressed at low to moderate levels in tissues in major physiological systems (central nervous system (CNS), endocrine, metabolic, gastrointestinal, immune, reproductive, structural) with particularly high levels in testis and white fat.

PubMed


 Coregulator Pages User Guide (updated Oct 2008)

At a Glance
Nomenclature
nuclear DNA-binding protein (C1D); Small unique nuclear receptor corepressor, nuclear DNA-binding protein (SUN-CoR)

Primary References
Zamir I, Dawson J, Lavinsky RM, Glass CK, Rosenfeld MG and Lazar MA (1997) Cloning and characterization of a corepressor and potential component of the nuclear hormone receptor repression complex. Proc Natl Acad Sci U S A 94, 14400-5. View Abstract | View PubMed

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