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Name
Thyroid receptor-associated protein-80
Symbol
TRAP80

Coregulator Pages User Guide (updated Oct 2008)

At a Glance
Nomenclature
Negative regulator of activated transcription complex, 70 kDa component (NAT-p70); Activator-recruited cofactor complex 77 kDa component (ARC77); Cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa (CRSP77); Thyroid receptor-associated protein-80 (TRAP80); Vitamin D receptor-interacting protein-77 (DRIP77); Cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa (CRSP6)

Primary References
Rachez C, Lemon BD, Suldan Z, Bromleigh V, Gamble M, Näär AM, Erdjument-Bromage H, Tempst P and Freedman LP (1999) Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. Nature 398, 824-8. View Abstract | View PubMed
Ito M, Yuan CX, Malik S, Gu W, Fondell JD, Yamamura S, Fu ZY, Zhang X, Qin J and Roeder RG (1999) Identity between TRAP and SMCC complexes indicates novel pathways for the function of nuclear receptors and diverse mammalian activators. Mol Cell 3, 361-70. View Abstract | View PubMed
Fondell JD, Ge H and Roeder RG (1996) Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc Natl Acad Sci U S A 93, 8329-33. View Abstract | View PubMed

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