JAB1

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Name
Jun activation domain-binding protein-1
Symbol
JAB1
JAB1, initially characterized as a coactivator of AP1, has been shown to potentiate the activity of several nuclear receptors.

Coregulator Pages User Guide (updated Oct 2008)

At a Glance Go to
Nomenclature
Jun activation domain-binding protein-1 (JAB1); COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) (COPS5)

Primary References
Chauchereau A, Georgiakaki M, Perrin-Wolff M, Milgrom E and Loosfelt H (2000) JAB1 interacts with both the progesterone receptor and SRC-1. J Biol Chem 275, 8540-8. View Abstract | View PubMed

Claret FX, Hibi M, Dhut S, Toda T and Karin M (1996) A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 383, 453-7. View Abstract | View PubMed


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