Cyclin D1

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Name
Cyclin D1
Symbol
Cyclin D1
D-type cyclins function as essential regulatory subunits of the cyclin-dependent kinases in mid-to-late G1 to regulate cell progression into S phase. Cyclin D1 has been shown to act as a bifunctional regulator of nuclear receptor-mediated transcription.

 Coregulator Pages User Guide (updated Oct 2008)

At a Glance
Nomenclature
Cyclin D1 (PRAD1: parathyroid adenomatosis 1) (CCND1)

Primary References
Zwijsen RM, Buckle RS, Hijmans EM, Loomans CJ and Bernards R (1998) Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1. Genes Dev 12, 3488-98. View Abstract | View PubMed
Motokura T, Bloom T, Kim HG, Jüppner H, Ruderman JV, Kronenberg HM and Arnold A (1991) A novel cyclin encoded by a bcl1-linked candidate oncogene. Nature 350, 512-5. View Abstract | View PubMed

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