BRCA1

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Name
Breast cancer type1 susceptibility protein (Breast cancer 1, early onset)
Symbol
BRCA1
BRCA1, a nuclear phosphorprotein encoded by a gene in which germline mutations are associated with susceptibility to breast and ovarian cancer, is a coregulator of several nuclear receptors.

 Coregulator Pages User Guide (updated Oct 2008)

At a Glance
Nomenclature
Breast cancer type1 susceptibility protein (Breast cancer 1, early onset) (BRCA1)

Primary References
Fan S, Wang J, Yuan R, Ma Y, Meng Q, Erdos MR, Pestell RG, Yuan F, Auborn KJ, Goldberg ID and Rosen EM (1999) BRCA1 inhibition of estrogen receptor signaling in transfected cells. Science 284, 1354-6. View Abstract | View PubMed
Narod SA, Feunteun J, Lynch HT, Watson P, Conway T, Lynch J and Lenoir GM (1991) Familial breast-ovarian cancer locus on chromosome 17q12-q23. Lancet 338, 82-3. View Abstract | View PubMed

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