PRIC285

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Name
Peroxisomal proliferator-activated receptor A interacting complex 285
Symbol
PRIC285

Overview

PRIC285 is a member of a multisubunit complex containing a variety of individually-characterized nuclear receptor coregulators, such as CBP, SRC-1, PGC-1α, TRAP100 and PBP. PRIC285 has been individually characterized as a coregulator in its own rght, as a coactivator for peroxisome proliferator-activated receptor-α (PPAR-α).

Expression

REA is expressed in a variety of physiological systems, including the metabolic (skeletal muscle, liver, kidney), gastrointestinal (colon), immune (spleen), reproductive (placenta), cardiovascular (peripheral blood leukocytes) and respiratory (lung) systems.

PubMed


 Coregulator Pages User Guide (updated Oct 2008)

At a Glance
Nomenclature
Peroxisomal proliferator-activated receptor A interacting complex 285 (PRIC285)

Primary References
Surapureddi S, Yu S, Bu H, Hashimoto T, Yeldandi AV, Kashireddy P, Cherkaoui-Malki M, Qi C, Zhu YJ, Rao MS and Reddy JK (2002) Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator. Proc Natl Acad Sci U S A 99, 11836-41. View Abstract | View PubMed

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